The serum protein electrophoresis test clarifies the components of the protein, which can reflect the degree of damage to the liver cells and the extent of the lesion. For example, in patients with liver disease and kidney disease, serum protein electrophoresis can reveal a decrease in albumin and an increase in globulin. And the degree of variation can also reflect the extent of liver damage. However, abnormal results on serum protein electrophoresis do not necessarily indicate a disease state. For example, babies, pregnant women, and vaccinated people can also have elevated globulins.