Sprained ankle in basketball can be treated by elevating the affected limb, applying cold compresses, using elastic bandages, and taking oral anti-inflammatory painkillers, etc. The fastest recovery is as follows: First, elevate the affected limb and apply cold compresses: before the swelling occurs, elevate the affected limb continuously and apply cold compresses continuously for three days to prevent serious swelling and relieve pain symptoms. Second, use elastic bandage: Before the swelling occurs, use elastic bandage to put pressure on the ankle joint, which can play the role of braking, fixing and pressure, and can inhibit the swelling and make the soft tissue repair gradually. Thirdly, oral anti-inflammatory and pain-relieving drugs: celecoxib, loxoprofen sodium, and oxymorphone tablets can clearly improve the clinical symptoms. After the above comprehensive treatment, the patient’s ankle sprain will be relieved quickly and will gradually recover in 1-2 weeks under normal circumstances. Patients can appropriately cooperate with functional exercises of the ankle joint, but not weight bearing.