Diclofenac sodium extended-release tablets are a kind of drugs with anti-inflammatory, analgesic and antipyretic effects, which are often used clinically for the treatment of various pains and fevers. Diclofenac sodium extended-release tablets have serious stimulation on the gastrointestinal tract, and long-term use may cause ulcers and bleeding in the gastrointestinal tract and even induce the risk of perforation. If severe abdominal pain occurs during taking the drug, or black stools appear frequently, it is recommended to go to the hospital for examination. Long-term use of diclofenac sodium extended-release tablets can affect blood clotting function and may induce hypertension or even induce myocardial infarction and stroke. Patients with cardio-vascular diseases should avoid taking them as much as possible. If more serious skin allergies, such as rash or exfoliative dermatitis, occur while taking them, it is also recommended to stop taking them immediately and go to the local hospital. Diclofenac sodium extended-release tablets may also damage vision. If blurred vision or double vision occurs, it is also recommended to go to the ophthalmology department of the local hospital for immediate examination.