After the first injection of the new crown vaccine, you can usually take medication, such as antihypertensive drugs, hypoglycemic drugs, lipid-lowering drugs, etc., but you need to avoid taking glucocorticosteroids and other drugs to suppress the immune ability. It is not an absolute contraindication to take medication after receiving the New Crown vaccine. For example, if the patient has high blood pressure, he/she can take antihypertensive drugs such as amlodipine, if he/she has diabetes mellitus, he/she can take hypoglycemic drugs such as acarbose, and if he/she has hyperlipidemia, he/she can take lipid-lowering drugs such as atorvastatin, etc. The above medications generally do not affect the effectiveness of the vaccine. However, certain drugs may have some effect on the effect of the new crown vaccine, such as prednisone, methylprednisolone and other glucocorticoid drugs, which can inhibit the body’s immune response and may reduce the response rate of the new crown vaccine. Therefore, do not blindly self-medicate after vaccination, if you need to use medication is recommended to consult a doctor.