Nephritic anemia, or renal anemia, is a symptom of anemia due to kidney disease and a common complication of chronic kidney disease. Treatment includes general treatment, iron supplementation, erythropoiesis-stimulating agent treatment, hypoxia-inducing factor proline hydroxylase inhibitor treatment and blood transfusion. 1. General treatment: appropriate labor, avoiding overwork; strengthening nutrition, avoiding foods that affect iron absorption, such as orange juice, wine, cola, coffee, strong tea, etc. 2. Iron supplementation: iron deficiency is common in chronic kidney disease, effective iron supplementation can improve the anemia symptoms of patients, at present, the clinic adopts oral or intravenous route of iron supplementation, such as ferrous sulfate, ferrous succinate, iron sucrose or iron dextrose. 3. Erythropoiesis stimulating agent treatment: such as gene recombinant human erythropoietin subcutaneous or intravenous administration, clinical application is more widely. 4. Hypoxia-inducible factor proline hydroxylase inhibitor therapy: such as roxarestat orally can effectively treat renal anemia and improve the body’s iron status. Intravenous iron supplementation is not necessary during treatment, or only oral iron supplementation. 5. Blood transfusion: Blood transfusion is not recommended under normal circumstances. If the degree of anemia is severe and obvious signs and symptoms have appeared, or hemodynamic instability, or patients with resistance to erythropoietin may consider blood transfusion therapy, but long-term transfusion therapy is not recommended. Renal anemia requires standardized clinical treatment, and it is recommended to consult a doctor to improve the treatment plan under the guidance of the doctor, and the above drugs should also be used under the guidance of the doctor.