Yellow semen can be treated by oral medication. It is important to clarify the cause of yellow semen. If yellow semen occurs because of long-term non-ejaculation, it is a physiological condition and does not require too much worry. If it is pathological, yellow semen due to prostatitis or seminal vesiculitis, antibiotic treatment, such as lincomycin, polymyxin B and rifampicin, is needed to achieve a therapeutic effect. Prostate fluid, fluid secreted by the epididymis, seminal vesicle gland fluid, and sperm secreted by the testicles, which are the components of male semen, and changes in semen in terms of color or odor can determine where there is a related problem. It is necessary to go to the hospital for semen examination or ultrasound examination, which can be carried out for exclusion, and oral medication can be used according to the disease.