The pain of appendicitis is typically dominated by metastatic lower right abdominal pain, which may be accompanied by fever, nausea, vomiting, diarrhea, and other manifestations of gastrointestinal infection. The appendix is located at the beginning of the colon and is predominantly found in the lower right abdomen where the body’s anatomy is organized. An attack of appendicitis results in acute congestion and edema of the appendix, leading to pain from inflammatory substances on the surface of the appendix that irritate the peritoneum. Since pain at the appendix is innervated by visceral nerves, it is not localized accurately and is prone to manifestations such as tugging pain. Typical appendicitis pain is: the first for the middle and upper abdomen hidden pain, after the pain gradually aggravated, and gradually transferred to the navel around, and finally fixed in the right lower abdomen Mai’s point, physical examination of the compression of the right lower abdomen presents pressure pain, rebound pain. If not actively and effectively treated at this time, the appendix perforation, the right lower abdomen peritoneal stimulation, can lead to abdominal pain subperitoneal gradually expand. Appendicitis can not be diagnosed simply by symptoms, after the appearance of metastatic right lower abdominal pain and other symptoms related to acute appendicitis, you need to carry out as soon as possible the appendix area ultrasound examination and laboratory tests, etc., a clear diagnosis needs to be treated as soon as possible. It is recommended to perform appendectomy as an emergency, and after the operation, intravenous penicillin and cefuroxime should be used for anti-infection treatment.