The third generation of test tube relative to the first generation and the second generation has some improvements, but do not need to follow blindly. The main advantage of the third generation of IVF relative to the first and second generation is the pre-implantation genetic screening, which means that before embryo implantation, 1-2 cells are taken out of the split-stage embryo or blastocyst for biopsy, and it has been examined whether it carries abnormal genes or there are chromosomal abnormalities. If there is a family history of genetic disease, it is recommended to do three generations of IVF to achieve eugenic purposes IVF technology does not become more advanced as the number of generations increases, and patients need to choose the appropriate treatment for different situations. The first generation of IVF refers to conventional in vitro fertilization embryo transfer, the second generation is monosperm cytoplasmic microinjection, and the third generation is preimplantation genetic screening, which all have different indications and need to be judged individually by doctors. Three generations of IVF have their own advantages and specificity, patients should not blindly follow.