Chronic obstructive pulmonary disease (COPD), also known as chronic obstructive pulmonary disease (COPD), is characterized by shortness of breath or dyspnea, in addition to chronic cough, sputum, wheezing and chest tightness. 1. Shortness of breath or dyspnea: COPD is a disease caused by persistent airflow limitation, therefore, its signature symptom is shortness of breath or dyspnea, which occurs only during exertion in the early stage, and with the development of the disease, shortness of breath may occur during daily activities or even when the patient is resting. 2. Chronic cough: COPD is mostly related to air pollution, smoking and other factors, under the action of external factors, which leads to the phenomenon of cough. 3. Coughing up sputum: patients with COPD may have secretions due to inflammatory stimuli, therefore, patients have the phenomenon of coughing up sputum, in addition, the amount of sputum can be increased in the acute exacerbation period. 4. Wheezing and chest tightness: some patients, especially those with severe disease, may have wheezing and chest tightness, which usually occurs after exertion. When the above symptoms occur, the patient should go to the hospital as soon as possible to get a clear diagnosis and early treatment.