Dry syndrome to check blood and urine routine, blood sedimentation, C-reactive protein, autoantibodies, globulin, dry keratitis test, salivary flow rate, parotid gland imaging, lip gland biopsy and other items. 1. Blood and urine routine, blood sedimentation, C-reactive protein: some patients with dry syndrome may have anemia, leukopenia, thrombocytopenia, increased blood sedimentation, increased C-reactive protein or renal tubular acidosis. 2. autoantibodies: dry syndrome is a diffuse connective tissue disease, more than 80% of patients have autoantibody ANA positive, or anti-SSA, anti-SSB autoantibodies positive, the former has higher sensitivity for diagnosis, the latter has higher specificity. 3. Globulin: patients with dry syndrome have mainly elevated IgG, which is hyperglobulinemia. A few patients have macroglobulinemia. 4. dry keratitis test: including Schirmer test, tear film break-up time, eye staining, etc., which can detect decreased tear secretion and help diagnosis. 5. Salivary flow rate: patients with dry syndrome have oral desiccation manifestations, and salivary flow rate examination can detect reduced salivary secretion. 6. Parotid angiography: parotid angiography in patients with dry syndrome can see irregular narrowing or dilatation of parotid ducts. 7. Lip gland biopsy: when there are inflammatory foci in the gland, such as lymphocyte aggregation >50 per 4mm^2, and ≥1 foci in the salivary gland tissues, it is a positive histopathological examination, which helps in the diagnosis of dry syndrome. Patients with dry syndrome should choose the examination items under the guidance of specialized physicians and follow the doctor’s instructions for examination and treatment.