Peripheral Arterial Disease (PDA), an important limb manifestation of atherosclerosis, is a disease of the lower extremities. With the improvement of the overall living standard of the society and the aging of the population, the incidence of lower extremity atherosclerosis is increasing, and hypertension, hypercholesterolemia, and smoking are important risk factors. The vast majority of atherosclerosis occurs in the lower extremities because the arteries of the lower extremities are long and thick and bear high pressure of blood, and there are more chances of internal and external damage to the arterial lining. The lower leg tibiofibular artery, femoral N artery and main iliac artery, the highest incidence of femoral N artery, lower extremity atherosclerosis occlusive disease atherosclerosis pathogenesis is complex, is the long-term comprehensive action of a variety of factors. The clinical symptoms of lower extremity atherosclerosis occlusive disease are mostly caused by thrombosis. The early symptoms of lower extremity atherosclerosis-occlusive disease PDA are intermittent claudication, weakening or disappearance of distal arterial pulsation, and later stages of lower extremity atherosclerosis-occlusive disease may include resting pain, significantly lower skin temperature, cyanosis, toe ulcers, gangrene, etc. The main diagnostic methods include DSA for lower extremity atherosclerosis-occlusive disease, ultrasound for lower extremity atherosclerosis-occlusive disease, CTA for lower extremity atherosclerosis-occlusive disease and MRA for lower extremity atherosclerosis-occlusive disease. Angiography is the “gold standard” for the diagnosis of PDA in lower extremity atherosclerosis-occlusive disease, and can accurately show the location, degree, collateral circulation, and hemodynamic changes of the stenosis/occlusion of the lower extremity atherosclerosis-occlusive disease. The medical treatment of lower extremity atherosclerosis and occlusive disease, such as hypotension, lipid lowering and antiplatelet aggregation, can only slow down the progression of lower extremity atherosclerosis and occlusion, but cannot fundamentally eliminate the stenosis and occlusion of lower extremity atherosclerosis and occlusion. Surgical endovascular debridement, artificial vessel replacement and bypass reconstruction for lower extremity atherosclerosis and occlusive disease are highly invasive and risky, especially not suitable for patients with lower extremity atherosclerosis and occlusive disease combined with serious cardiovascular and cerebrovascular disorders and diabetes mellitus. Endovascular intervention for lower extremity atherosclerosis has the advantages of minimally invasive, simple operation, precise efficacy and repeatable operation, which is the development direction of diagnosis and treatment of vascular diseases. Ultrasound and laser angioplasty for lower extremity atherosclerosis-occlusive disease are the newest hot spots of peripheral interventional technology for lower extremity atherosclerosis-occlusive disease in recent years, which can open the occluded lesions in the long segment of smaller arteries and are especially suitable for the treatment of occluded lesions below the diabetic carotid artery.