Lumbar disc herniation sciatic nerve pain may lead to nerve edema, muscle atrophy, muscle strength of both lower limbs, sensory abnormalities and so on. 1. Nerve edema: sciatic nerve pain belongs to the manifestation of lumbar disc herniation compressing the nerve. Prolonged compression of the nerve may lead to edema and degeneration of the pinched nerve, causing radiating pain from the thigh to the calf and even the ankle in the form of burning, cutting pain, numbness and other syndromes. 2. Muscle atrophy: The pain develops further along the nerve course, and muscle atrophy may occur due to spasm and lack of blood and oxygen in the muscles of the lower limbs. 3. Abnormal muscle strength and sensation of both lower limbs: prolonged ischemia and hypoxia of muscles and nerves may result in weakness of both lower limbs, deep and superficial sensory disturbances, and manifestations such as foot drop and intermittent breaking of the line, further aggravation of nerve damage, ischemic necrosis of the nerve, and even paraplegia below the innervated area may occur as a serious consequence. If the symptoms of lumbar intervertebral disc herniation sciatic nerve pain occur, it is recommended that the patient actively cooperate with the doctor, early standardized treatment, in order to reduce the adverse effects of the disease.