Bone marrow matching is a test to check whether the patient’s human leukocyte antigen genes match the leukocyte antigen genes of the person donating the bone marrow. The price of a bone marrow match is usually around$2,400 per case. The match of a bone marrow match is of great importance to the patient’s susceptibility to rejection and the occurrence of graft-versus-host disease after receiving a bone marrow transplant. This is because only if the leukocyte antigen genes are perfectly matched, the success rate of bone marrow transplantation will be high, the incidence of graft-versus-host disease will be low, and the bone marrow transplantation results will be good. In clinical practice, human leukocyte antigen genetic matches are classified as fully compatible, partially compatible and semi-compatible. In China, due to the high population of only children, semi-compatible transplants are becoming more and more common and have achieved good treatment results.