People who stay up late often will have stomach pain and often stay up late will have endocrine disorders. Not sleeping when it is time to sleep, the body organs need to consume energy, it will produce hunger, increased secretion of gastric acid will lead to damage to the gastric mucosa, over time chronic gastritis, gastroduodenal ulcer, patients appear repeated stomach pain, bloating, acid reflux, heartburn, belching and other indigestion symptoms. When patients have stomach pain and discomfort, they should undergo gastroscopy in time to rule out the possibility of gastric cancer in addition to gastritis and gastroduodenal ulcer. In daily life, light, warm, soft and easily digestible food should be given, three meals should be regular and quantitative, regular work and rest, no late night and proper exercise to enhance physical fitness.