Long-term staying up late leads to disturbance of the patient’s biological clock, which can cause insomnia and affect the patient’s health, so it is recommended to make timely adjustments. Patients should first adjust their lifestyles, develop regular habits of work and rest, go to bed at regular intervals and get up on time. During the daytime, they can participate in more outdoor sports activities, which can improve their physical fitness and improve the symptoms of cerebral nerve dysfunction. Patients must drink a glass of hot milk at night, bubble their feet, go to bed at the right time, and do not do things in bed that are not related to sleep, do not read cell phones or play games in bed. This biological clock can be adjusted with the help of drugs, such as oral sleeping pills, such as diazepam, eszopiclone, alprazolam, dexrazopiclone and other drugs, generally taken orally for about a week, the patient’s sleep situation and biological clock disorders can be corrected.