If you take antidepressant medication, the effects usually start to appear in about 2 weeks, and it takes about 6-8 weeks of taking the medication for the effects to be noticeable, as well as being able to reduce feelings of unhappiness and stabilize the condition. Why is this so? Because antidepressants are not like medications for somatic diseases, all antidepressants, such as the commonly used sertraline, paroxetine, fluoxetine, venlafaxine, etc., require a certain amount of time after the patient has taken the medication in order to reach the concentration of the onset of action. In particular, these are drugs that treat neurotransmitter disorders in the brain of patients with depression, and its pharmacological mechanism also suggests that these drugs need a long period of time to be able to work, especially to reach the brain within the brain to balance the brain’s neurotransmitters, all need a process.