Mannix refers to the levonorgestrel intrauterine sterilization system. Oral cephalosporin antibiotics can be useful to prevent infection after levonorgestrel IUD removal. Levonorgestrel intrauterine device system use period is 5 years, for the placement of the period of the device has reached the need to replace the person, the emergence of adverse reactions by the conservative treatment is ineffective, should be taken out, it is a uterine operation, there is a risk of uterine infection after the operation, the operation should be strictly aseptic operation, the use of antibiotics to prevent infection after the operation, after the operation, pay attention to personal hygiene and regular follow up, so the application of cephalosporin after the operation is useful. Contraindications to the removal of the birth control device are: suffering from serious systemic diseases, such as heart, liver, kidney failure, coagulation disorders, inflammation of the reproductive tract, two weeks after the removal of the operation prohibit coitus, pelvic baths, if there is an increase in vaginal bleeding, abdominal pain and other discomforts, at any time the hospital for medical attention.