Causes of elevated total bilirubin and indirect bilirubin: 1, mainly considered as a result of abnormal liver system diseases, such as viral hepatitis, cirrhosis, hepatocellular liver cancer, acute jaundice hepatitis, toxic hepatitis, cholestasis syndrome, etc. The liver is an important place for metabolizing and circulating bilirubin in the body, once the liver has abnormalities, it will affect the normal operation of the liver, and part of the bilirubin cannot be metabolized, thus circulating Once the liver is abnormal, it will affect the normal operation of the liver and some of the bilirubin cannot be metabolized, thus causing an increase of bilirubin in the body; 2, hemolytic anemia, blood type incompatibility transfusion, cholelithiasis and other diseases; 3, because bilirubin is also distributed in the digestive system, abnormalities in the digestive system such as pancreatitis, pancreatic head cancer, gallbladder stones, peptic ulcer and other diseases will lead to abnormal bilirubin; 4, physiological high, such as neonatal jaundice, overeating, strong alcohol consumption will also lead to a slight increase.