Coronary heart disease is an atherosclerotic heart disease of the coronary arteries, in which lipid deposition in the intima leads to the formation of intravascular plaques, blocking blood flow and causing ischemia in cardiomyocytes, with clinical manifestations of angina attack or myocardial infarction. Controlling the risk factors of coronary heart disease not only reduces the incidence of coronary heart disease, but also delays the occurrence of peripheral vascular sclerosis. It has been reported that patients with coronary artery disease may show red palms or bruises in cold condition with or without edema in hands and feet due to peripheral vascular sclerosis and poor blood circulation causing peripheral blood circulation stagnation. The use of drugs to improve peripheral circulation, such as Beraprost sodium tablets or Mizarin, can help improve peripheral circulation, prevent blood clots and reduce the occurrence of coronary complications.