Hepatitis B virus nucleic acid test is divided into qualitative and quantitative, qualitative results are expressed as negative and positive, and quantitative results are the number of viruses, expressed as specific values, which are used to determine the speed of viral replication and infectiousness, and to evaluate the efficacy of drugs. Hepatitis B virus DNA is the sign of viral replication and infectiousness, and is the most direct, specific and sensitive indicator of viral infection, which can be both qualitative and quantitative. It can be used to determine the level of infectiousness and the direction of disease progression of hepatitis B virus carriers. Hepatitis B surface antigen is positive and hepatitis B DNA is negative, which basically indicates that the virus replication speed is very slow and the infectiousness is very weak. If hepatitis B virus DNA is positive for a long period of time, the virus is actively replicating and infectious, and it is easy to develop to cirrhosis and liver cancer. Hepatitis B virus quantitative results, generally more than 3 times 10 less than 5 times 10, which is a mild increase. If the quantification is more than 10-5 times less than 10-7 times, this is a moderate elevation, and for DNA quantification more than 10-7 times, this is a severe elevation. Hepatitis B DNA needs to be interpreted by a medical professional and the decision to initiate antiviral therapy will be made on a case-by-case basis. If hepatitis B DNA is positive or higher than the lower limit of detection, you should go to a regular hospital and avoid self-treatment, so as not to delay the diagnosis and treatment of the disease.