The treatment of uneven endometrial echogenicity depends on the cause of the cause before it can be treated symptomatically. For example, if the endometrial echogenicity is uneven due to incomplete shedding of the endometrium after a menstrual period, it can be observed for 1-2 months and reviewed in detail 3 days after menstruation. If persistent failure to return to normal, oral medication such as anti-estrogen, which is a form of progestin treatment, should be taken to help the endometrium shed a lot and see if it returns to normal. If the endometrial echogenicity is uneven due to surgical operation, abortion, or diagnostic curettage. In this case, the recovery of the uterus needs to be a process, and it may take a 3-month interval to determine if it is normal. If it does not return to normal, a hysteroscopy is needed to determine if the uterine morphology has returned to normal, and depending on the situation, the necessary surgery, such as electrodesiccation or re-scraping, will be performed. If the echogenicity is uneven due to endometrial polyps and endometrial hyperplasia. The endometrial scraping procedure under hysteroscopy should be performed to scrape out a part of the endometrium, and pathological tests should be performed to determine the endometrial tissue of which period it belongs to, and then it can be regulated with medication cycle according to the situation.