Sartan class of blood pressure-lowering drugs, also known as angiotensin II receptor antagonist, belongs to the clinical first-line antihypertensive drugs, commonly used sartan class of blood pressure-lowering drugs mainly include chloretin, valsartan, irbesartan, timosartan, olmesartan, and candesartan and so on. Angiotensin Ⅱ receptor antagonist, its antihypertensive effect is mainly through the blockade of tissue angiotensin Ⅱ receptor subtype, angiotensin receptor Ⅰ, can block angiotensin Ⅱ vasoconstriction, sodium retention, and remodeling effect, so as to be able to reduce the blood pressure of hypertensive patients. Its inhibition of remodeling can also be used to treat myocardial remodeling in chronic heart failure, myocardial remodeling after myocardial infarction, and hypertensive-induced myocardial hypertrophy, which can improve the prognosis of patients.