The common side effects of progesterone shots in early pregnancy are nausea, dizziness, abnormal liver function, and some very rare reactions. Progesterone injection is a natural progestin, clinically used to treat menstrual irregularities, preeclampsia, luteal insufficiency and habitual abortion treatment, which has a basic adverse effect on fetal development. After the application of progesterone injection, some pregnant women may experience nausea, dizziness, liver function abnormalities, etc. Rarely, allergic reactions urticaria, breast discomfort, etc.. There are contraindications to the application of progesterone injection. When symptoms such as preeclampsia occur, pregnant women who need fertility preservation treatment are advised to consult a hospital in time and apply fertility preservation drugs under the guidance of a professional doctor.