The most common cause is heart disease, including myocardial ischemia caused by coronary artery disease, people will feel empty in the chest, as well as weakness, shortness of breath and other symptoms, which can be relieved after rest. Also, if there is an arrhythmia, such as frequent premature ventricular contractions, there will be an empty feeling in the chest, as if the heartbeat suddenly slowed down this discomfort. If heart disease causes a feeling of empty chest, you can go to the hospital for a timely examination, and the diagnosis can be made clearly by doing electrocardiogram and blood tests, and then symptomatic treatment can be given. The empty chest may also be caused by stomach diseases, including gastric ulcer, atrophic gastritis, gastric mucosal erosion and other diseases, which can lead to the feeling of empty chest. The main reason is that after the gastric mucosal lesions will cause the stomach to contract and spasm, or the stomach mucosal irritation of this uncomfortable feeling, often manifested as the chest empty, uncomfortable.