Elevated free thyroxine and thyroid stimulating hormone at the same time need to be suspected of pituitary adenoma or thyroid hormone resistance syndrome and other diseases. For pituitary adenomas, surgical treatment is the mainstay, but for prolactinomas, drug treatment is preferred, such as bromocriptine, etc. For thyroid hormone resistance syndrome, antithyroid medication and glucocorticoid therapy can be given according to the patient’s condition. Pituitary adenoma belongs to the saddle region occupying lesions, most of them are benign, common prolactinoma, growth hormone adenoma, adrenocorticotropic hormone adenoma, etc. Surgical resection is the main means of treatment for pituitary adenomas (except for prolactin adenoma), and prolactin adenomas are mainly treated with medication, such as bromocriptine. Thyroid hormone resistance syndrome is often caused by mutations in the T₃ receptor gene, and the abnormal secretion of TSH stimulates the growth of the thyroid gland, so that the secretion of T₃, T₄ can not inhibit the release of TSH, so it can be given to the antithyroid drug therapy to reduce thyroxine, and can also be used to inhibit the secretion of TSH by growth inhibiting hormone, etc. In conclusion, if it is found that the thyroid gland has been damaged, the main means of treatment is oral bromocriptine. In conclusion, if abnormal thyroid function is detected, it is recommended to go to the hospital immediately for consultation, make a clear diagnosis, follow the doctor’s instructions, and according to the cause of the disease, choose whether to have surgical treatment or to give the appropriate drug treatment.