The curability of a glomerular filtration rate of 72.8 ml/min depends largely on the cause of its decline. If it is caused by physiological factors or acute kidney injury, it is usually curable after correcting the reversible cause. If it is due to pathological causes such as chronic renal failure and other diseases, irreversible damage to the kidney occurs, and it is usually not curable. Under normal circumstances, the glomerular filtration rate is between 80 and 120 ml/min. Glomerular filtration rate 72.8 ml/min is mildly decreased. Glomerular filtration rate is affected by age, gender, weight, etc. If the patient is an elderly person, although the glomerular filtration rate is reduced, but there is no abnormality in urinary routine, renal function and other indexes, at this time, it is a normal physiological phenomenon, and there is no need for treatment. If the glomerular filtration rate decreases due to acute kidney injury, after correcting the reversible cause of the disease, renal function will gradually recover, and this situation may be cured; if the glomerular filtration rate decreases due to chronic renal failure and other diseases, irreversible damage to the kidneys occurs, and renal function can not be restored, and this situation can not be cured usually. If patients find that the glomerular filtration rate decreases, it is recommended to go to regular hospitals in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.