Dapoxetine and tadalafil tablets can be taken at the same time under the premise of meeting the indications and eliminating contraindications, but the specific use of medication should be carried out in accordance with medical advice. At present, there is no drug study shows that Dapoxetine and tadalafil tablets will have significant interference with each other’s therapeutic effect, so only from the point of view of the principle of drug action, the two drugs can be taken at the same time. However, it should be noted that some studies have suggested that there is a risk of decreasing the body’s standing endurance when the two drugs are used together, so caution should be exercised. It is also important to note that Dapoxetine is a 5-hydroxytryptamine reuptake inhibitor for men aged 18 to 64 years old with premature ejaculation, this drug is prohibited for those who are allergic to it or are using drugs such as thioridazine, ketoconazole, phenelzine, etc., and headache, nausea and other adverse reactions are also possible in the course of the use of the drug. Tadalafil tablets belong to the type 5 phosphodiesterase inhibitors, suitable for the treatment of erectile dysfunction in men over 18 years of age, the drug is prohibited for those who are allergic to it, the presence of active heart disease, or are using nitroglycerin and other nitrate drugs, adverse reactions include headache, blurred vision, and so on. To summarize, there is a need for Dapoxetine and tadalafil tablets, must be under the guidance of a doctor to regulate the use of medication, do not blindly take the drug or increase or decrease the dosage of their own, so as not to cause adverse consequences.