Plasma donations are generally harmless, but frequent donations should be avoided. Plasma is an important part of human blood, and the extraction of plasma is generally not harmful to the human body. Under normal circumstances, a healthy person should not donate more than 600 grams of plasma at one time (including anticoagulant), basically, it will not cause too much impact on the body, the body will make blood in time to replenish the body, and after a period of time, it will be restored to the level of the pre-donation of blood. Generally, the interval between two blood donations is at least 14 days. However, it is important not to donate plasma too often. Frequent plasma donation can neither guarantee the quality of blood nor ensure your own health. If sub-standard plasma is provided, it will cause harm to the recipient and may cause the recipient to receive little effect from the plasma transfusion. Plasma donation is recommended to be done in a regular medical institution, and if you feel unwell, you need to consult a doctor promptly.