Neuroblastoma differentiation type refers to the type of neuroblastoma’s degree of differentiation, which can determine the degree of malignancy of the tumor to some extent. Neuroblastoma is a common extracranial tumor in children and is a neuroendocrine tumor. Its main differentiation types are undifferentiated, moderately differentiated, and highly differentiated. Generally speaking, the lower the degree of differentiation, the higher the malignancy, and the higher the degree of differentiation, the lower the malignancy. Neuroblastoma can occur in many parts of the body, such as the neck, chest, abdomen, and pelvic nerve tissue. The symptoms are not obvious in the early stage, so children should be observed actively in their daily life, and should consult a doctor if they have symptoms such as abdominal distension, pale skin, or difficulty in walking, etc. If neuroblastoma has been diagnosed, it is important to consult a doctor. If neuroblastoma is diagnosed, treatment should be carried out according to the doctor’s instructions. At present, depending on the degree of malignancy, surgery or chemotherapy or radiotherapy are the main treatment methods.