The treatment of atrophic gastritis with glandular intestinalization includes causative treatment, such as omeprazole, amoxicillin, metronidazole, bismuth potassium citrate anti-Helicobacter pylori treatment, and supplementation of multivitamins; symptomatic treatment, such as rabeprazole acid suppression, to improve the symptoms of abdominal pain and acid reflux; and also to improve the diet and so on. 1. Anti-causal treatment: those who have Helicobacter pylori infection should be treated with anti-Helicobacter pylori, and can use omeprazole, amoxicillin, metronidazole, bismuth potassium citrate as prescribed by the doctor; for those who are caused by duodenal-gastric reflux, gastric mucosal protectants such as aluminum phosphate gel and other gastric mucosal protective agents and gastrointestinal dynamics drugs such as domperidone can be used; those who are lack of gastric mucosal trophic factor can be supplemented with multivitamins or vitamin B12. 2. Symptomatic treatment: Omeprazole, rabeprazole and other acid-suppressing drugs can be used to inhibit the secretion of gastric acid and improve the symptoms of abdominal pain and acid reflux; domperidone and other gastrointestinal dynamics can be used to improve the gastrointestinal dynamics of the insufficiency of enzyme preparations to improve the digestive enzymes of the insufficiency of abdominal distension. 3. Improve the diet: pay attention to supplemental nutrition, eat a reasonable combination, avoid eating moldy, smoked, pickled food, avoid spicy stimulating food, avoid rough and hard food. Atrophic gastritis with intestinal epithelial hyperplasia is closely related to gastric cancer, so it must be highly valued, followed up for a long time, and rechecked regularly to prevent cancer. Medications should be used under the guidance of a doctor.