Elevated blood sedimentation and sedimentation equation k-values include physiologic and pathologic increases. An increase in the rate of blood sedimentation causes an increase in the k value of the sedimentation equation. Generally, the acceleration of blood sedimentation rate can be divided into physiological acceleration and pathological acceleration. 1. Physiologic acceleration: seen during menstruation, pregnancy and childbirth from the third month of pregnancy to the first month after delivery, as well as the elderly over 60 years of age. 2. Pathological acceleration: seen in connective tissue disease, acute inflammation, severe tissue destruction, active stage of rheumatic fever, anemia, malignant tumor, abnormal globulinemia and leukemia. If there is a high blood sedimentation and sedimentation equation k value of the test results, can not accurately determine the cause, but also need to be combined with the characteristics of the medical history, other test results to make an accurate judgment, it is recommended that under the guidance of the doctor to clarify the cause of the disease, targeted treatment.