Fistula in the esophagus can be treated with enteral therapy, anti-infection, and gastrointestinal parenteral nutrition, as follows: 1. It needs to be patented and drained in time, and it can be done by abdominal puncture and thoracic puncture, and enteral therapy can be used by using transnasal jejunum nutritional tubes in time; 2. It is given with broad-spectrum antibiotics to control the bacterial infection, and transfused with human albumin to improve the immunity of the body, and to promote the healing of the tissues; 3. If it is not possible to perform enteral nutrition, and even If it is impossible to perform enteral nutrition, even complete parenteral nutrition is needed to ensure the body’s energy supply and promote tissue healing. Fistula in esophagus usually occurs after surgery for esophageal cancer or gastric cardia cancer, and the anastomosis at the anastomosis between esophagus and jejunum heals poorly, causing digestive fluid to enter into thoracic cavity or subdiaphragmatic abdominal cavity, and the patient will have chills, fever, and even pus chest in serious cases.