Osteoarthritis should be treated with fast-acting symptom relievers (e.g., acetaminophen), slow-acting symptom relievers, and cartilage protectors (e.g., dextrose, chondroitin sulfate, etc.), and medications should be used only in accordance with your doctor’s instructions. 1. Fast-acting symptom relievers: such as acetaminophen, which can be used for analgesic treatment, and non-steroidal anti-inflammatory drugs (NSAIDs), which are also commonly used for symptom control. Weak opioids may be considered in patients with acute pain who are not adequately relieved by the first 2 medications or have contraindications. In addition, injections of sodium hyaluronate can improve synovial fluid quality and reduce pain sensitivity. 2. Osteoarthritis slow-acting drugs and chondroprotective agents: these drugs generally have a slow onset of action, such as glucosamine, bisacodyl ryanodine, chondroitin sulfate, etc. However, the above three types of drugs can be effective in improving the symptoms of osteoarthritis, relieving the patient’s pain, and improving the role of joint function. If the drug treatment is not obvious, surgical treatment can be considered, etc. Osteoarthritis patients need to be actively diagnosed and treated, and the adverse effects of the drugs need to be noted.