Nine out of ten fat people will snore, so is this snoring considered a disease? Snoring, also known as OSAHS (sleep apnea syndrome), can cause neurological dysfunction, catecholamine, endothelin and renin-angiotensin system dysregulation, endocrine dysfunction and hemodynamic changes due to recurrent episodes of hypoxia and hypercapnia, resulting in multi-organ and multi-system damage throughout the body and seriously affecting human health. How is OSAHS defined? Sleep apnea is defined as a cessation of inspiration for more than 10 seconds > 30 times per night during 7 hours of sleep, or an AHI ≥ 5 times/hour. Obesity-induced metabolic diseases are intrinsically linked to each other and can cause serious damage to the patient’s body, and only sleep apnea syndrome, a seemingly insignificant disease, has many hazards. A cardiovascular impact 1, hypertension: sleep apnea syndrome is an important factor in the occurrence and development of hypertension, at least 30% of hypertensive patients combined with obstructive sleep apnea syndrome, 45% to 48% of patients with sleep apnea syndrome have hypertension. This hypertension loses the normal circadian rhythm of change, mostly manifested as high blood pressure when waking up in the morning, not easy to control with drugs, after treatment of sleep apnea syndrome can mostly return to normal. 2, coronary artery disease: coronary artery angiography shows that there is a single or multiple coronary artery stenosis of patients with coronary artery disease, 35% combined with sleep apnea syndrome, such patients more angina attack at night, taking nitroglycerin class drugs can not be relieved, and the treatment of sleep apnea syndrome can be relieved. 3, heart failure: sleep apnea syndrome can cause or aggravate heart failure in patients with heart disease, mainly due to myocardial ischemia, hypoxia and pressure changes in the thoracic cavity caused by inspiration pause, which increases the load on the heart and decreases cardiac output. A patient was hospitalized for recurrent acute left heart failure and later diagnosed with severe sleep apnea syndrome after polysomnography, and cardiac function recovered quickly after treatment with continuous positive pressure ventilation. 4, arrhythmias: about 80% of patients with sleep apnea syndrome have significant bradycardia, 57% to 74% have premature ventricular beats, and 10% have second-degree atrioventricular block. Such arrhythmias are the main cause of sudden death in patients. Therefore, people with arrhythmias should think about whether they are suffering from sleep apnea syndrome. Sleep apnea syndrome is a group of potentially fatal sleep apnea disorders that are easily complicated by arrhythmias, hypertension, and even whistle failure and sudden death. It has been estimated that 3,000 people worldwide die from this disease every day. 269 patients were followed by Thorpy and 43 (16%) died within 7 years, 71% of which were due to cardiovascular disease. In untreated patients, the 5-year mortality rate was reported to be 11-13%, and for those with aspiration apnea index >20, the 8-year mortality rate was 37%, while for those with apnea index <20, the mortality rate was only 4%. 198 patients were retrospectively analyzed by Partinen, and the 5-year mortality rate was 11% for 127 patients who only did bariatric treatment. Therefore, effective treatment can improve the quality of life of patients and prolong their lives. Second, the damage to the kidney obstructive sleep apnea syndrome can be combined with proteinuria or nephrotic syndrome, triggering renal impairment due to the closure of the patient's upper airway, increased negative thoracic pressure, increased right heart reflux, ischemia, pulmonary vasoconstriction, increased right heart load, resulting in right atrial dilation, stimulating increased secretion of atrial natriuretic factor, decreased sodium reabsorption rate in the proximal renal tubules of the kidney, urinary osmolality and renal tubular The clinical manifestations are increased nocturia and nocturnal urination. The clinical manifestations are increased nocturia and swelling, and in severe cases, a series of manifestations of renal insufficiency may appear. With the decrease of blood oxygen saturation, the EEG often shows arousal pattern, which shows non-rapid eye movement sleep, and the decrease of rapid eye movement sleep and other sleep structure disorders, leading to the decrease of sleep efficiency. There may be pre-sleep hallucinations, unconscious behavior, and twitching and spasms of the limbs after sleep. Brain damage caused by hypoxia and circulatory disorders can result in mental retardation, memory loss and personality change, etc. Fourth, the impact on the mental system 1, cognitive dysfunction: the patient's cognitive function is fully affected, of which attention, concentration, complex problem-solving ability and short-term memory impairment is most obvious. The reduced alertness of patients with obstructive sleep apnea syndrome increases the incidence of motor vehicle accidents. The majority of patients with obstructive sleep apnea syndrome have fallen asleep while driving, and 54% have fallen asleep while driving and been involved in a car accident. These patients complained of frequent nodding off while driving, sometimes hitting trees, sometimes hitting walls, or hitting pedestrians, often having to stop the car to wake up for a while, and being more likely to doze off while driving on the highway. Generally speaking, the more severe the obstructive sleep apnea syndrome, the higher the risk of a car accident, so it should be treated promptly. 2, mental disorders: depression, anxiety, hypochondria and other symptoms are the most important. 56% of patients have depression, 38% have hypochondria, 29% have conversion hysteria. There are also individual patients with simple type of paranoid psychosis, manic psychosis, etc. Behavioral abnormalities are not uncommon, such as restlessness during sleep, moving of hands and feet, and sometimes sleepwalking. V. Effects on the blood system Low blood oxygen can stimulate the kidneys to secrete erythropoietin, causing secondary erythropoietin, leading to increased blood viscosity, slow blood flow and increased chances of cerebral thrombosis. In addition, it can accelerate atherosclerosis and increase the occurrence of vascular diseases. Effects on the endocrine system The growth hormone secreted by the anterior pituitary gland is mainly released during rapid eye movement sleep. In children with obstructive sleep apnea, the release of growth hormone is reduced to varying degrees due to the reduction of rapid eye movement sleep, which is one of the factors affecting the slow growth of the sick child. Seven, the impact on sexual function Sleep apnea patients can develop sexual dysfunction for several reasons: 1, hypoxemia and hypercapnia impair brain function, central excitability decreases, sexual activity is inhibited; 2, the disease patients have decreased responsiveness, attention, observation, difficulty in reaching orgasm during sexual intercourse, the duration is short; 3, causing hypoxia and androgen production disorders in the sexual organs.