Left humeral cystic change is usually benign. Left humeral cystic change may be caused by heredity, trauma or inflammation, etc. It is a benign lesion, if there is no obvious pain and discomfort, it can be without special treatment. The larger cystic changes are mainly surgical resection, the smaller ones do not affect the physical activities, can be observed dynamically, usually pay attention to warmth and rest, and regular radiographs for review. Some patients with cystic changes of the left humerus may have a tendency to malignant transformation after local stimulation, if the growth is rapid, then ultrasound examination should be carried out, biopsy or surgical resection if necessary. If the left humerus cystic degeneration patients have physical discomfort, they should go to the hospital in time, after a clear diagnosis by the doctor to arrange the treatment program, in order to avoid delaying the condition.