If a lymphoma patient has a fever, different approaches should be taken depending on the cause. Lymphoma itself can cause fever, and fever is the most common one among the B symptoms of lymphoma. The treatment is symptomatic treatment and tumor control at the same time, and the fever caused by lymphoma in this case is essentially tumor fever. If the body temperature does not exceed 38.5℃, physical methods such as alcohol baths and ice packs can be used to lower the temperature. In a few cases, the body temperature may exceed 38.5℃, and oral antipyretic drugs are needed to reduce the body temperature rapidly along with physical cooling. Most importantly, anti-tumor treatment measures such as radiotherapy and chemotherapy should be used to control tumor growth in order to finally relieve fever. Patients with lymphoma have poor resistance, especially after chemotherapy with reduced white blood cells, and are prone to infectious fever. In this case, while applying physical cooling and medication to reduce fever, sensitive antibiotics should be used to control infection, and it is also important to draw blood culture to find pathogenic bacteria, and this test helps to guide anti-infection treatment. In conclusion, if a patient with lymphoma has fever, the first step is to determine the cause of the fever. If infection can be ruled out, follow the tumor heat treatment. If there is evidence of infection, anti-infective treatment should be administered immediately and the fever should be treated as an infectious fever.