Gurgling in throat in late stage of lung cancer may be caused by compression of recurrent laryngeal nerve or combined infection. 1. Pressure on recurrent laryngeal nerve: Lung cancer is a malignant tumor of lungs, which will increase gradually with the development of its condition, and in the late stage, it may press the recurrent laryngeal nerve and block the respiratory tract, leading to unsmooth breathing, which may cause gurgling in the throat, usually accompanied by hoarseness of voice and other manifestations. 2. Combined with upper respiratory tract infection: patients with advanced lung cancer usually need to take comprehensive treatments such as chemotherapy and radiotherapy, which will impair normal immune function and lead to low immunity, easily causing infection, forming infection in throat, trachea and lungs, which manifests itself as fever, cough, and phlegm, thus leading to gurgling in the throat. It is recommended to carry out blood routine, lung X-ray, CT and other related examinations to clarify the cause and then take targeted treatment.