Patient conditions vary and taking 2 capsules of regorafenib daily may or may not be effective. Regorafenib is used to treat metastatic colorectal cancer that has received prior chemotherapy based on a drug such as fluorouracil or gastrointestinal mesenchymal tumor disease that has received prior imatinib mesylate. Usually, the recommended dose of the drug is 4 capsules per day, and taking 2 capsules does not allow the drug to have the desired therapeutic effect. Some patients should adjust the dose of the drug in time after the occurrence of intolerable toxic reactions, in which case taking 2 capsules per day is effective, but the specific therapeutic effect varies from person to person. People who are allergic to this drug are prohibited from taking it, and patients should take this drug under the guidance of a professional doctor.