The stomach grumbling at night is related to physiological factors such as cold abdomen and hunger, and is also considered to be related to acute enteritis, intestinal torsion, ulcerative colitis and so on. 1. Physiological factors: when the patient’s abdomen is cold, in a state of hunger, mental overstress, it is easy to cause stomach grumbling at night. 2. Acute enteritis: Pathogenic microorganisms infection, improper diet, etc. can cause acute enteritis. Typical symptoms of patients include abdominal pain, diarrhea, nausea and vomiting, hyperactive bowel sounds, etc., which can be manifested as stomach grumbling. 3. Intestinal torsion: mainly due to the torsion of the intestinal tube and its mesentery. Patients will have abdominal pain, abdominal distension, nausea and vomiting and other symptoms, which can also cause some patients’ stomach grumbling. 4. Ulcerative colitis: the etiology is not clear, may be related to immune factors, genetic factors, intestinal microecological changes. Disease can cause some patients stomach grumbling, but also easy to accompany diarrhea, mucous pus and blood stools, abdominal pain, abdominal distension and other symptoms. The stomach grumbling at night is also considered to be related to medication, intestinal adhesions, intussusception, intestinal obstruction, dysentery, etc. It is recommended that the patient seek medical attention in a timely manner.