Joint pain at the base of the right thumb is commonly caused by the following: First, sprain of the 1st metacarpophalangeal joint. Sprain of the 1st metacarpophalangeal joint can occur when playing basketball and other rival sports, and the patient feels pain and limited movement of the joint, and examination reveals obvious swelling of the injured joint. Treatment includes intermittent local cold compresses for 10-20 minutes each time, 6-8 times a day, which can relieve the local swelling and pain symptoms of the joint, along with metacarpophalangeal joint immobilization and braking for 1-2 weeks. Second, stenosing tenosynovitis, stenosing tenosynovitis can be formed by repeated wear and tear of the thumb flexor tendon and tendon sheath, with clinical manifestations of hard nodules palpable at the root of the thumb with local pressure pain, limited flexion and extension of the thumb and symptoms of entrapment, treatment methods include local closed injection therapy, extracorporeal shock wave therapy and surgical tendon release and tendon sheath removal.