Clinically, the most likely site of embolism in atrial fibrillation is the brain, whether it is caused by valvular disease or non-valvular atrial fibrillation. The reason for this is that in atrial fibrillation, the contractile function of the atrium is weakened, and a thrombus is formed in the appendage wall, and once the thrombus is dislodged, cerebral embolism may be caused. In addition to the brain, the arteries of the upper and lower extremities and the mesenteric arteries may cause embolism. Therefore, clinically, patients with atrial fibrillation should be resuscitated as much as possible. Patients who can’t be resumed without contraindications to anticoagulation need to take anticoagulant drugs regularly, while controlling the heart rate, maintaining cardiac function, and regular checkups.