Gallbladder removal and colon cancer are two systems. Gallbladder removal is usually required for gallstones combined with impaction, obstruction, biliary tract infection, acute cholecystitis or obstructive purulent cholangitis, gallbladder polyps, gallbladder cancer, bile duct cancer, and so on. The function of gallbladder is to concentrate and store bile, and the secretion of bile is mainly in the liver, and a small part is in the bile ducts. Therefore, although the removal of gallbladder will affect the discharge of bile to a certain extent, it will not hinder the secretion of most of the bile, so it still has some functions, mainly the bile ducts and liver play the function of secretion of bile. Colon cancer mainly depends on the location of the cancer, and different surgical methods can be chosen according to the location, for example, colorectal resection and anal fistula can be chosen for low location, and normal defecation function can be preserved for high location.