The treatment of chronic gonorrhea, i.e. chronic lymphocytic leukemia, includes chemotherapy, immunotherapy, chemoimmunotherapy, molecular targeted therapy, hematopoietic stem cell transplantation, and treatment of complications.
1. Chemotherapy
(1) Alkylating agents: such as nitrogen mustard phenylbutyrate, which is used for patients who are older, cannot tolerate chemotherapy with other drugs or have complications.
(2) Purine analogs: e.g. fludarabine, pentostatin, cladribine, etc.
(2) Immunotherapy: Rituximab is a human-mouse chimeric anti-CD20 monoclonal antibody, which is effective for expressing CD20 such as chronic lymphocytic leukemia.
3. Chemoimmunotherapy: Rituximab combined with chemotherapeutic drugs can produce synergistic anti-tumor effects and improve the survival rate of patients.
4. Molecular targeted therapy: such as ibrutinib, which has been used in the first-line treatment and salvage treatment of patients, and has few side effects.
5. Hematopoietic stem cell transplantation: It is used for second-line treatment of high-risk or refractory patients, but there are many related complications.
6. Complications of treatment
(1) Recurrent infections: immunoglobulin can be infused.
(2) Idiopathic thrombocytopenic purpura: can be treated with glucocorticoids.
(3) Giant spleen or obvious lymph node enlargement: radiation therapy can be considered.
Patients with chronic gonorrhea should not take medication on their own, but should go to the hospital in time and receive standardized treatment under the guidance of a doctor. All of the above mentioned drugs should be used in accordance with medical advice.