High uric acid, knee pain, but the pain has certain characteristics, often with a sudden onset of knee redness, swelling, pain, and accompanied by a significant increase in local skin temperature, and the nature of the pain is very intense. Generally speaking, there is a certain self-limiting nature, and the knee pain can improve on its own without any drug treatment, and it will enter an intermittent period for a long time, that is, the joint will not be red, painful or swollen. For knee pain caused by high blood uric acid, patients can take oral colchicine for anti-inflammatory and pain relief. At the same time, in order to prevent the pain from coming back, during the interval when the joint is not painful, patients need to take continuous uric acid-lowering medication, for example, they can take febuxostat orally.