Simple hyperuricemia has no symptoms, but without lifestyle improvement or systematic treatment, a series of symptoms will appear as the disease progresses. The most common is gout attacks, where high uric acid forms urate crystals that are deposited in the joints, leading to gout attacks and redness, swelling, heat and pain in the joints. There is also kidney damage, where uric acid crystals are deposited in the kidneys or form uric acid stones, which can lead to kidney damage, which can manifest as oliguria or even acute renal insufficiency. Eye lesions, where uric acid crystals are deposited in the subcutaneous tissue of the eyelids, can cause blepharitis or recurrent conjunctivitis. Severe gout can also develop gout stones, which can lead to joint deformities and even fractures, and hyperuricemia can also increase the risk of coronary heart disease, stroke, hypertension, and diabetes.