Leg neuralgia is mainly due to sciatica caused by nerve compression in the leg or lumbar spine disease. After leg neuralgia occurs, patients can take oral non-steroidal anti-inflammatory drugs to relieve the symptoms. These drugs can effectively eliminate local sterile inflammation, common NSAIDs include diclofenac sodium extended-release tablets, celecoxib capsules, meloxicam, etc. Patients can also take some oral nerve-nourishing drugs, such as vitamin B1, vitamin B12, methylcobalamin, etc., to relieve the symptoms of leg nerve pain. In addition, patients need to pay attention to local warmth, avoid cold and overexertion, and when pain is obvious, they need to rest in bed to reduce nerve edema, so as to relieve the pain symptoms.