Calf soreness and weakness feel very tired mostly refers to calf soreness and weakness, fatigue, common causes are overwork, muscle deficiency, potassium and calcium deficiency, myofasciitis and so on. 1. Excessive exertion: usually heavy exercise, stress, long-term late night, etc., can cause physiological calf weakness, generally can be relieved after rest. 2. Insufficient muscle power: If the lack of exercise usually leads to mild atrophy of calf muscles, the symptoms of calf weakness can appear after the decline of muscle power. 3. Potassium and calcium deficiency: unbalanced diet, resulting in insufficient intake of potassium ions and calcium ions or a large loss of potassium ions after diarrhea can cause calf weakness and fatigue. 4. Myofasciitis: aseptic inflammation that occurs in the muscles and fascia, mostly caused by trauma, overwork, etc. The common symptoms are muscle pain, soreness and weakness. There are more causes of soreness, weakness and fatigue in the calves, which may also be related to viral infections, lumbar disc herniation, varicose veins in the lower limbs and other diseases. If the symptoms continue to be unrelieved, it is recommended to consult a doctor in time to clarify the cause of the disease and carry out targeted treatment.