Pain next to the bladder may be caused by cystitis, bladder stones, nephritis and other diseases. 1. Cystitis: Inflammatory lesions of the bladder usually caused by bad habits, pathogen infection and other factors. Inflammatory mediators stimulate the bladder mucosa, then there will be pain next to the bladder, accompanied by frequent urination, urinary urgency, lower abdominal pain symptoms. 2. Bladder stones: usually due to age factors, pathogenic microbial infections and other factors related to the bladder stones, if the bladder stones are too large, it will cause pressure on the organs near the bladder, and pain occurs. 3. Nephritis: usually related to pathogen infection, autoimmune deficiency, genetic factors and other factors. Patients with inflammatory lesions in the kidneys may experience pain next to the bladder, accompanied by edema, abnormal kidney function and other symptoms. Patients with pain next to the bladder may also have other causes, and should seek medical treatment in time and choose the appropriate method for treatment.