Marfan’s Syndrome Aortic Replacement is a surgical procedure performed on patients with Marfan’s Syndrome. Marfan’s syndrome often involves the cardiovascular system and can present with aortic aneurysms as well as closure insufficiency, followed by entrapment aneurysms caused by degeneration of the middle layer of the aorta, which require replacement surgery. Marfan’s syndrome is an autosomal dominant disorder that runs in families. The most life-threatening complications are cardiovascular complications, mainly aortic aneurysms, aortic coarctation, and aortic insufficiency. Patients with significant dilatation of the aortic root, with or without symptoms, require prophylactic surgery. Commonly used surgical procedures include aortic root replacement, which is designed to prevent massive bleeding, and aortic valve replacement, which replaces the diseased aortic valve with a mechanical or biologic valve for therapeutic purposes. Patients with Marfan’s syndrome, which is a genetic disorder, require standardized treatment under the supervision of a physician.