Facial stem cell filler is a facial filler with stem cells in combination with fat tissue. As long as a small amount of filler is performed, the ideal effect of wrinkle removal can be achieved. Generally, there will be no infection, rejection and other reactions, and the safety is high and the effect is long-lasting. However, there are certain hazards of stem cell filling surgery, as follows: 1. tissue necrosis: if the stem cells are not supplied with sufficient blood after filling, it can lead to ulceration before the fat survives and pus, resulting in tissue necrosis; 2. tissue liming: mostly due to insufficient blood supply after filling with stem cells, the fat becomes hard, which may lead to liming; 3. unevenness of tissue: It is caused by uneven filling of stem cells; 4.Skin pigmentation: If bruising or swelling is serious after surgery, iron in the bruised area will adhere to the skin surface and oxidize to brown; 5.Tissue asymmetry: The main reason is the different cell survival rate on both sides; 6.Sagging of skin: It often happens when the filling amount is too much.